• Lupus is one of the most difficult diseases to diagnose precisely. But a simple new blood test can now rule out lupus with a high level of certainty.
  • About 1.5 million Americans have lupus (or SLE), an auto-immune disease that causes fatigue, headaches, swollen joints and many other symptoms. Could lupus be the cause of your symptoms? SLE-key can help your doctor find out.

SLE-key

SLE-key® is a molecular diagnostic test developed by ImmunArray to support a physician’s ability to rule-out a diagnosis of Systemic Lupus Erythematosus (SLE). SLE-key® works by determining the pattern of circulating antibodies to an array of antigens which are printed on ImmunArray’s proprietary iCHIP®. This pattern is compared to SLE affected and healthy control patterns. Proprietary analytic algorithms are then used to determine the likelihood of the patient being affected with SLE, along with a probability score.

The validated SLE-key®, developed based on autoantibody fingerprints from 250 affected and 250 healthy females, has been shown to exclude SLE during differential diagnosis with >90% sensitivity and >70% specificity.

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